Histology. Episode 5: Structure of Areolar Connective Tissue

Cells:

Fibroblasts: These are the predominant cells and are responsible for synthesizing the extracellular matrix components.
Macrophages: Involved in immune response and phagocytosis.
Mast cells: Contain granules with histamine and heparin, playing a role in inflammatory responses.
Other cells like lymphocytes and plasma cells may also be present.
Extracellular Matrix (ECM):

Ground Substance: This is a gel-like substance that fills the space between cells. It includes water, glycoproteins, and proteoglycans.
Fibers:
Collagen Fibers: Provide strength and support.
Elastic Fibers: Provide elasticity and flexibility.
Reticular Fibers: Thin fibers that form a mesh-like network, contributing to the tissue's structural framework.
Blood Vessels:

Areolar tissue contains a rich supply of blood vessels, ensuring that nutrients and gases can easily diffuse to and from the cells.
Nerve Endings:

Nerve endings may be present, allowing for sensory perception and response to stimuli.
Function:

Areolar connective tissue serves several functions, including providing support and elasticity to organs, facilitating the movement of nutrients and waste products between blood vessels and cells, and participating in the body's defense against infection and inflammation.
Location:

It is widely distributed throughout the body, found beneath the skin (subcutaneous tissue), around organs, blood vessels, and nerves.